Ciuclan, L: search on Z-Library

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1

Genetic ablation of PI3Kγ results in defective IL-17RA signalling in T lymphocytes and increased IL-17 levels

Harris, Stephanie J., Ciuclan, Loredana, Finan, Peter M., Wymann, Matthias P., Walker, Christoph, Westwick, John, Ward, Stephen G., Thomas, Matthew J.

Journal:

European Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

2

Reply

Ciuclan, Loredana, Thomas, Matthew

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2012

Language:

english

File:

PDF, 54 KB

english, 2012

3

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 â¢ San Francisco, California - ()] A29. PATHOGENESIS OF PULMONARY HYPERTENSION - Imatinib Attenuates Hypoxia-Induced PAH Pathology Via Reduction In Serotonin Through Inhibition Of Tryptophan Hydroxylase 1 Expression

Ciuclan, Loredana I., Hussey, Martin, Duggan, Nicholas, Burton, Victoria J., Good, Robert, Beach, Sarah, Jones, Peter, Fox, Roy, Konstantinova, Irena, Bonneau, Olivier, Rowlands, David, Pearce, Andrew

Year:

2012

File:

PDF, 20 KB

2012

4

Disruption of the Smad7 gene enhances CCI4-dependent liver damage and fibrogenesis in mice

Jafar Hamzavi, Sabrina Ehnert, Patricio Godoy, Loredana Ciuclan, Honglei Weng, Peter R. Mertens, Rainer Heuchel, Steven Dooley

Journal:

Journal of Cellular and Molecular Medicine

Year:

2008

Language:

english

File:

PDF, 1.02 MB

english, 2008

5

Hepatocyte-Specific Smad7 Expression Attenuates TGF-β–Mediated Fibrogenesis and Protects Against Liver Damage

Steven Dooley, Jafar Hamzavi, Loredana Ciuclan, Patricio Godoy, Iryna Ilkavets, Sabrina Ehnert, Elke Ueberham, Rolf Gebhardt, Stephan Kanzler, Andreas Geier, Katja Breitkopf, Honglei Weng, Peter R. Me

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 19.45 MB

english, 2008

6

699 TGF-β ENHANCES ALCOHOL DEPENDENT HEPATOCYTE DAMAGE VIA DOWNREGULATION OF ALCOHOL DEHYDROGENASE I

L. Ciuclan, S. Ehnert, I. Ilkavets, H.-L. Weng, H. Gaitantzi, H. Tsukamoto, K. Breitkopf, S. Dooley, M.V. Singer

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 89 KB

english, 2009

7

A Novel Murine Model of Severe Pulmonary Arterial Hypertension

Ciuclan, Loredana, Bonneau, Olivier, Hussey, Martin, Duggan, Nicholas, Holmes, Alan M., Good, Robert, Stringer, Rowan, Jones, Peter, Morrell, Nicholas W., Jarai, Gabor, Walker, Christoph, Westwick, Jo

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2011

Language:

english

File:

PDF, 1.61 MB

english, 2011

8

TGF-β/Smad Signaling in the Injured Liver

Breitkopf, K, Godoy, P, Ciuclan, L, Singer, M V, Dooley, S

Journal:

Zeitschrift für Gastroenterologie

Year:

2006

Language:

english

File:

PDF, 269 KB

english, 2006

9

Profibrogenic transforming growth factor-β/activin receptor–like kinase 5 signaling via connective tissue growth factor expression in hepatocytes

Hong-Lei Weng, Loredana Ciuclan, Yan Liu, Jafar Hamzavi, Patricio Godoy, Haristi Gaitantzi, Stefan Kanzler, Rainer Heuchel, Uwe Ueberham, Rolf Gebhardt, Katja Breitkopf, Steven Dooley

Journal:

Year:

2007

Language:

english

File:

PDF, 4.01 MB

english, 2007

10

302 TGF-BETA-DEPENDENT PROLIFERATION ARREST OF HEPTOCYTES AND DUCTULAR REACTION CONTRIBUTE TO HBV-ASSOCIATED LIVER FIBROGENESIS VIA NOTCH SIGNALING

H.-L. Weng, J. Li, L. Ciuclan, C. Meyer, T. Huang, P. Mertens, M. Singer, S. Dooley

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 46 KB

english, 2009

11

Treatment with Anti–Gremlin 1 Antibody Ameliorates Chronic Hypoxia/SU5416–Induced Pulmonary Arterial Hypertension in Mice

Ciuclan, Loredana, Sheppard, KellyAnn, Dong, Liqun, Sutton, Daniel, Duggan, Nicholas, Hussey, Martin, Simmons, Jenny, Morrell, Nicholas W., Jarai, Gabor, Edwards, Matthew, DuBois, Gerald, Thomas, Matt

Journal:

The American Journal of Pathology

Year:

2013

Language:

english

File:

PDF, 2.55 MB

english, 2013

12

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 â¢ Denver Colorado - ()] C61. PULMONARY HYPERTENSION: EXPERIMENTAL MODELS II - The Roles Of TPH1, Serotonin And PDGF Within A Novel Murine Model Of Pulmonary Arterial Hypertension

Ciuclan, Loredana I., Bonneau, Olivier, Hussey, Martin, Duggan, Nicholas, Thomas, Lorraine, Rowlands, David, Westwick, John, Thomas, Matthew J.

Year:

2011

File:

PDF, 21 KB

2011

13

279 BONE MORPHOGENETIC PROTEIN (BMP)-9: A NEW MEMBER OF THE TGF-β SUPERFAMILY WHICH IS SECRETED BY ACTIVATED HEPATIC STELLATE CELLS

K. Breitkopf, A. Müller, L. Ciuclan, E. Wiercinska, P. Ten Dijke, S. Dooley

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 50 KB

english, 2009

14

S153 Bone morphogenetic protein receptor-II regulates pulmonary artery endothelial cell barrier function: relevance to heritable pulmonary arterial hypertension

Burton, V. J., Ciuclan, L. I., Holmes, A. M., Rodman, D., Walker, C., Budd, D. C.

Journal:

Year:

2010

Language:

english

File:

PDF, 279 KB

english, 2010

15

TGF-β enhances alcohol dependent hepatocyte damage via down-regulation of alcohol dehydrogenase I

Loredana Ciuclan, Sabrina Ehnert, Iryna Ilkavets, Hong-Lei Weng, Haristi Gaitantzi, Hidekazu Tsukamoto, Elke Ueberham, Nadja M. Meindl-Beinker, Manfred V. Singer, Katja Breitkopf, Steven Dooley

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 1.42 MB

english, 2010

16

Identification of compounds acting as negative allosteric modulators of the LPA 1 receptor

Ellery, Jonathan, Dickson, Louise, Cheung, Toni, Ciuclan, Loredana, Bunyard, Peter, Mack, Stephen, Buffham, William J., Farnaby, William, Mitchell, Philip, Brown, Daniel, Isaacs, Richard, Barnes, Matt

Journal:

European Journal of Pharmacology

Year:

2018

Language:

english

File:

PDF, 945 KB

english, 2018

17

Activity of the Estrogen-Metabolizing Enzyme Cytochrome P450 1B1 Influences the Development of Pulmonary Arterial Hypertension

White, K., Johansen, A. K., Nilsen, M., Ciuclan, L., Wallace, E., Paton, L., Campbell, A., Morecroft, I., Loughlin, L., McClure, J. D., Thomas, M., Mair, K. M., MacLean, M. R.

Journal:

Year:

2012

Language:

english

File:

PDF, 3.64 MB

english, 2012

18

E microRNA-140-5p and SMURF1 Regulate Pulmonary Arterial Hypertension

Rothman, Alexander MK, Arnold, Nadine D, Pickworth, Josephine A, Iremonger, James, Ciuclan, Loredana, Allen, Robert, Guth-Gundel, Sabine, Southwood, Mark, Morrell, Nicholas W, Thomas, Matthew, Francis

Journal:

Year:

2016

Language:

english

File:

PDF, 67 KB

english, 2016

19

105 NOTCH SIGNALING PLAYS A CRITICAL ROLE IN EXPERIMENTAL AND HUMAN LIVER FIBROGENSIS

S. Dooley, Y. Liu, I. Ilkavets, H. Shen, V. Zimmer, R.M. Bohle, C. Zhu, C. Xu, C. Yu, C. Meyer, L. Ciuclan, C. Stump, A. Müller, T. Huang, Y. Li, F. Lammert, M.V. Singer, P.R. Mertens, H.-L. Weng

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 50 KB

english, 2010

20

Imatinib Attenuates Hypoxia-induced Pulmonary Arterial Hypertension Pathology via Reduction in 5-Hydroxytryptamine through Inhibition of Tryptophan Hydroxylase 1 Expression

Ciuclan, Loredana, Hussey, Martin J., Burton, Victoria, Good, Robert, Duggan, Nicholas, Beach, Sarah, Jones, Peter, Fox, Roy, Clay, Ieuan, Bonneau, Olivier, Konstantinova, Irena, Pearce, Andrew, Rowla

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2013

Language:

english

File:

PDF, 2.28 MB

english, 2013

21

T5 MicroRNA-140–5p Regulates Disease Phenotype in Experimental Pulmonary Arterial Hypertension via SMURF1

Rothman, AMK, Arnold, ND, Pickworth, JA, Iremonger, J, Ciuclan, L, Allen, R, Guth-Gundel, S, Southwood, M, Morrell, NW, Francis, SE, Rowlands, DJ, Lawrie, A

Journal:

Year:

2015

Language:

english

File:

PDF, 64 KB

english, 2015

22

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 â¢ San Francisco, California - ()] B63. EXPERIMENTAL MODELS IN PULMONARY HYPERTENSION I - Imatinib As A Therapy For Pulmonary Arterial Hypertension - Insights Into Mechanism Of Action From Rodent Models

Thomas, Matthew J., Bonneau, Olivier, Ciuclan, Loredana, Duggan, Nicholas, Rowlands, David, Grieve, Jenny, Baker, Andrew, MacLean, Mandy, Jarai, Gabor, Westwick, John

Year:

2012

File:

PDF, 177 KB

2012

23

Targeting the serotonin pathway for the treatment of pulmonary arterial hypertension

Thomas, Matthew, Ciuclan, Loredana, Hussey, Martin J., Press, Neil J.

Journal:

Pharmacology & Therapeutics

Year:

2013

Language:

english

File:

PDF, 896 KB

english, 2013

24

238 TRANSFORMING GROWTH FACTOR (TGF)-β INCREASES THE ADVERSE EFFECTS OF ETHANOL ON HEPATOCYTES: TWO INTERACTING SIGNAL TRANSDUCTION PATHWAYS LEADING TO APOPTOSIS AND FIBROSIS IN THE LIVER

H. Gaitantzi, L. Ciuclan, P. Godoy, M.V. Singer, S. Dooley, K. Breitkopf

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 48 KB

english, 2009

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